Журнал Современные проблемы науки и образования 2070-7428 Общество с ограниченной ответственностью "Издательский Дом "Академия Естествознания" ART-21135 ДЕФИЦИТ ВИТАМИНА Д ВО ВРЕМЯ БЕРЕМЕННОСТИ И ГРУДНОГО ВСКАРМЛИВАНИЯ Васильева Э.Н. Vasileva E.N. kafedra_pediatrii@mail.ru Денисова Т.Г. Denisova T.G. ipiuv@medinform.su Гунин А.Г. Gunin A.G. kafedra_pediatrii@mail.ru Тришина Е.Н. Trishina E.N. glvr@gkb1.org ФГБОУ ВПО « Чувашский государственный университет имени И.Н. Ульянова» FSBEI HPE “The Chuvash State University named after I.N. Ulyanov” АУ Чувашии «Институт усовершенствования врачей» Минздравсоцразвития Чувашии AI of Chuvashia “Postgraduate Doctors’ Training Institute” HealthCare and Social Development Ministry of Chuvashia БУ «Городская клиническая больница № 1» Минздравсоцразвития Чувашии BI “Municipal clinical hospital No.1” HCSD Ministry of Chuvashia 05 04 2015 4 455 455 This is an open-access article distributed under the terms of the CC BY 4.0 license. https://science-education.ru/ru/article/view?id=21135

Витамин Д – активный компонент, который участвует во многих метаболических процессах, в поддержании адекватного уровня врожденного иммунитета, что играет весомую роль в профилактике хронических аутоиммунных заболеваний, а также в поддержании адекватного иммунного ответа на чужеродные агенты, что способствует профилактике онкологических заболеваний. Выявлена связь дефицита витамина Д с длительным течением многих заболеваний. Доказано, что во многих странах у женщин репродуктивного возраста, беременных и кормящих матерей имеется высокая распространенность дефицита витамина Д, который часто сопровождается негативными последствиями для женщины, плода и новорожденных детей. Согласно одной из гипотез, в результате событий окружающей среды во время беременности, внутриутробно, происходит эпигенетическое программирование плода – индуцирование конкретных генов и геномных путей, которые контролируют развитие плода и обусловливают последующий риск заболеваний. Восполнение дефицита витамина Д может быть одной из важных профилактических программ здравоохранения.

Vitamin D is an active ingredient, which is involved in many metabolic processes. Vitamin D is involved in providing an adequate level of innate immunity, that is essential for the prevention of chronic autoimmune diseases, as well as developing an adequate immune response to a foreign agent, that is important for cancer prevention. It has been revealed the dependence of long-term run of many diseases on vitamin D deficiency. It is proved that in many countries here is a high prevalence of vitamin D deficiency in the women of fertile age, pregnant and nursing mothers, which is often accompanied by a negative impact on women, fetus and newborn. According to one hypothesis, the environment events during pregnancy, in uterine period there is fetal epigenetic programming that is induction of specific genes and genomic pathways that control the development of the fetus and cause subsequent risks of diseases. Supplementing of vitamin D deficiency can be one of the most important preventive health programs.

 дефицит витамина Д беременность иммунитет костная система эпигенетическое программирование плода vitamin D deficiency pregnancy immune system skeletal system epigenetic programming of the fetus

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